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They also suggest that with proper support and resources, smokers with mood and anxiety disorders could quit successfully as a result of these policies. Reference: The effects of reduced nicotine content cigarettes on biomarkers of nicotine and toxicant exposure, smoking behavior and psychiatric symptoms in smokers with mood or anxiety disorders: A double-blind randomized trial by Jonathan Foulds, Susan Veldheer, Gladys Pachas, Shari Hrabovsky, Ahmad Hameed, Sophia I

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The same study established that one e-cigarette puff results in a glycerol exposure of 348495 mg/m 3 [57], which is close to the levels reported to cause airway irritation in rats (662 mg/m 3 ) [58]