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Metabolism Essential to all forms of life, the nicotinamide coenzyme NAD + is synthesized in the body from four precursors that are provided in the diet: nicotinic acid, nicotinamide, nicotinamide riboside, and tryptophan ( Figure 1 )

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METHODS Study design and population The National Health and Nutrition Examination Survey (NHANES) is a nationally population-based survey to assess the nutritional and health status of US children and adults