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Among mothers under 20 years of age, that percentage climbs to 45% In the US, 20% of women under the age of 25 smoke during pregnancy Lead study author Professor Allan Hackshaw said that while literature on the harms of smoking during pregnancy have long focused on risks such as low birth weight or miscarriage, information on increased risks for birth defects has been lacking - because no one really knew which birth defects were associated specifically with smoking