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New tobacco and nicotine products, such as vapes (e-cigarettes), pouches, and heated tobacco products, require authorization by the Food and Drug Administration (FDA) through a highly burdensome process, the premarket tobacco product application (PMTA)

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There may be a positive angle in e-cigarettes enhancing chances of smoking cessation, but there is no evidence-based study demonstrating its safety & efficacy of e-cigarettes (22)

Other active ingredients are also beneficial to use in this context