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Acne Inversa Acne inversa (also known as Hidradenitis suppurativa) is a relatively common inflammatory skin condition that usually causes sores to develop in areas where skin rubs against the skin such as the armpits, groin, and under the breasts

It has been shown that SIRT3 can suppress inflammation by decreasing the expression levels of NF - kB , high mobility group box 1 ( HMGB1 ), c - Jun , c - Fos , cyclooxygenase-2 ( COX2 ), TNF - , IL - 1 and IL - 6 [149]