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Access this article Data availability N/A Abbreviations DRESS: Drug rash with eosinophilia and systemic symptoms EBV: Epstein-Barr virus IM: Infectious mononucleosis RegiSCAR: Registry of Severe Cutaneous Adverse Reactions URTI: Upper respiratory tract infection VRESS: Virus reactivation with eosinophilia and systemic symptoms References Metterle L, Hatch L, Seminario-Vidal L (2020) Pediatric drug reaction with eosinophilia and systemic symptoms: a systematic review of the literature