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More serious B12 deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes

Maintain healthy Skeletomuscular System

However, in two-hit mouse models, exposure to EIII followed by the administration of autoantibodies leads to target cell damage, including endothelial apoptosis and hemorrhage (Figure 2, lower panel) [119,120,122,147,148]

Gene-level modulation: Pickart & Margolina 2018 documented activity across ~4,000 human genes, with fibroblast expression patterns shifting closer to younger cells