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Weeks 6 to 12: optimization The extended phase is about fine-tuning

Disclosure of interest: Prof Dippel reports funding from the Dutch Heart Foundation, Brain Foundation Netherlands, The Netherlands Organisation for Health Research and Development, and Health Holland Top Sector Life Sciences & Health and unrestricted grants from Penumbra Inc., Stryker European Operations BV, Medtronic, Thrombolytic Science, LLC, and Cerenovus for research, all paid to institution

Moderate alcohol isnt a direct contraindication, but heavy use can counteract the anti-inflammatory and healing effects peptides are meant to support

Xie C, Prahl A, Ericksen B, Wu Z, Zeng P, Li X, Lu WY, Lubkowski J, Lu W: Reconstruction of the conserved b-bulge in mammalian defensins using D-amino acids