Importantly, MB levels of parabens and benzophenones were found to be lower than those measured in PB serum (Matsumoto et al., 2007), providing evidence for a blooduterine barrier: a physical and/or metabolic partition that may restrict certain compounds from reaching the endometrium, potentially via glucuronidation-mediated metabolism and increased excretion of endocrine-disrupting chemicals
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Ibel H, Endres W, Hadorn HB, Deufel T, Paetzke I, Duran M, Kennaway NG, Gibson KM
Here, we establish an integrated regulatory network linking supramolecular transformations with engineered genetic pathways and metabolic responses