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Keywords: peptide, immune tolerance, lupus, regulatory T cells, immunotherapy, cytokine, chemokine Introduction Autoimmune rheumatic diseases carry a significant burden of morbidity and mortality and have a substantial economic impact on both individuals and the society as a whole

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Research (168) indicates that the Fe 2+ directly induced by myoglobin metabolism may lead to lipid peroxidation in proximal tubule epithelial cells, which could be an important pathogenic mechanism of rhabdomyolysis-induced acute AKI