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10.1007/s12264-018-0269-8 151 WhittleB
These results are in line with previous findings indicating that inhibition of mitochondrial complex I synergizes with mitochondrial antioxidants in impairing cancer cell fitness, supporting the notion that complex I is a dominant determinant of viability ( Figure 2 2.3 DPI synergizes with vincristine and MitoQ in reducing cell viability of MNA NB cells Finding synergistic drug combinations allows for combining drugs at lower concentrations, which is an important strategy for enhancing therapeutic efficacy while minimizing adverse effects
Once the vials seal is broken and the sterile environment is compromised, theres nothing in the solution to prevent bacterial growth
Researchers note that while both drugs significantly reduce body weight, their underlying mechanisms differ in scope
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