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Sharma et al ., 2006, "The Etiology of Hypertension in the Metabolic Syndrome Part Two: The Gene-Environment Interaction"

It triggers ferroptosis in gastric cancer cells by manipulating the miR-4893p/SLC7A11 pathway, thereby hindering cancer cell proliferation ( Curcumin, a component derived from turmeric and used in traditional Chinese medicine, has been discovered to cause iron accumulation, GSH depletion, and lipid peroxidation in non-small cell lung cancer (NSCLC) cells

Downstream Signaling Pathways Following target engagement, several downstream signaling cascades have been reported in experimental models

"Cysteine/Glutathione Deficiency: A Significant and Treatable Corollary of Disease"