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An acute exposure to ultraviolet radiation may lead to several inflammatory responses, skin erythema, rash, irritation and skin ulcers [81], on the other hand, chronic UV exposures can produce carcinoma and photo-aging [82]

The consequences of loss of muscle function are far reaching and include decrease of motor control and overall fitness, development of functional limitations and impairment, and long term disability

There is a risk of intoxication, especially in patients with liver disease, in chronic alcoholism, in patients with chronic malnutrition, and in patients receiving enzyme inducers