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Vitamin B12 injections are most clinically appropriate in cases of confirmed vitamin B12 deficiency, malabsorption syndromes including pernicious anaemia or post-gastric surgery, significant symptoms where rapid restoration of vitamin B12 levels is required, or failure of oral supplementation due to poor absorption

Rather than acting via the ghrelin receptor, CJC-1295 directly activates the GHRH receptor the primary physiological driver of pituitary GH production