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Clinical decision support, management, risk detection, prevention, prognosis and diabetes diagnosis (including medical image analysis and subtype classification) are expected to be increasingly dependent on artificial intelligence [154,155,156,157,158]
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Nat Med J 2:122 Sanders VR, Millar NS (2023) Potentiation and allosteric agonist activation of 7 nicotinic acetylcholine receptors: binding sites and hypotheses
In addition, peptides (such as FRAF) form a multi-level inhibition network by targeting MITF, TYR and TYRP1/2, and its mechanism goes beyond single target intervention: FRAF forms hydrogen bonds with ASP431 and ALA384 of MITF, blocking the combination of MITF and target gene promoters (such as TYR and TYRP1) and inhibiting the expression of melanin synthesis-related enzymes
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