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However, because it has been shown in clinical trials to be highly effective for weight loss, doctors often prescribe it off-label for this purpose

It also contributes to blood pressure and autonomic cardiovascular regulation, enhancement of immune function, and reduction of inflammation in the gastrointestinal tract

First, reduce exposure to environmental toxins, pollutants, and chemicals whenever possible

Additionally, if gut permeability is indeed increased in ME/CFS patients, microbes and antigens may be able to cross the epithelial barrier into surrounding tissue and blood, potentially crossing the BBB and altering the HPA axis (443)