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In clinical studies, it has been shown to have beneficial effects on skin aging, muscular homeostasis, diabetes, Alzheimer disease, cardiovascular disease, and osteoporosis

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Therefore, given the rarity of suicidal or self-harming behaviors, the limited sample size of the RCT, and the inherent limitations of retrospective studies, comprehensive research with long-term follow-up and rigorous mental health assessments is needed to clarify the potential risks and benefits