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The three most frequently cited examples in peer-reviewed literature are alcohol, tobacco, and cannabis

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[51] Electroencephalography (EEG) shows somewhat more persistent alpha waves of slightly lower frequency than usual

They deserve protection too. Several other tobacco companies prohibit those under 18 from a number of particularly hazardous tasks in tobacco farming, but none of the companies have policies sufficient to protect all children under 18 from dangerous work, Human Rights Watch said