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Specifically, bioactive molecules such as leukotrienes and prostaglandins produced during AA metabolism via LOX and COX can directly or indirectly increase NOX complex activity, leading to the catalysis of intracellular ROS synthesis, including O , thereby participating in the regulation of oxidative stress and cell signalling pathways [15]

Cuproptosis: cellular and molecular mechanisms underlying copper-induced cell death

Molecules 27:3413

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